Róisín McManus studied natural science with a specialization in neuroscience for her undergraduate degree in Trinity College Dublin, Ireland, where she graduated with a first class honours (2010). Following this, she dida PhD under the joint supervision of Prof. Marina Lynch and Prof. Kingston Mills in Trinity College Dublin, Ireland, studying the effect of infection on the brain with age and in Alzheimer’s disease (2010-2015).
Róisín worked as a post doc in the Lynch lab on biomarker development in dementia (2015), before joining Prof. Michael Heneka’s lab at the DZNE in Bonn, Germany (2015-2021). During her post doc with Prof. Heneka, Róisín investigated new roles for the NLRP3 inflammasome in contributing to Alzheimer’s disease, in addition to developing novel methods to inhibit NLRP3 inflammasome activation.
Róisín joined Prof. Eicke Latz’s group at the DZNE and the III in 2021, where she was a senior postdoctoral researcher and an Alzheimer Forschung Initiative (AFI) project leader, overseeing a team of scientists together with Prof. Latz.
In 2024 Róisín was awarded a Fellowship from the DZNE to establish herown research group. Her work examines how immune signalling influences microglial metabolic reprogramming, and looks to the role of metaflammation in driving neurodegenerative disease.
Skiing, travelling and piano
2024-present Member of the Excellence Cluster ImmunoSensation2, University of Bonn
2018-2019 Member of the Helmholtz Advance mentoring program
2017-present IndependentGrant reviewer for the French National Research Agency and the European Joint Program on Rare Diseases
2015-present IndependentManuscript reviewer at 16 Journals including Alzheimer's and Dementia, Brain Behavior and Immunity, Cell Death and Disease
2014 Dean of Students’ Roll of Honor, Trinity College Dublin
2010 B.Sc.(Mod), Trinity College Dublin, Ireland. Graduated with 1st class honours
Group Leader at DZNE
Senior Postdoctoral Scientist in the group of Prof. Eicke Latz, DZNE and Institute of Innate Immunity, Bonn, Germany.
Postdoc in the lab of Prof. Michael Heneka, DZNE, Bonn, Germany.
Postdoc in the lab of Prof. Marina Lynch, Trinity College Institute of Neuroscience, Trinity College Dublin, Ireland.
Research PhD, Department of Biochemistry and Immunology, Trinity College Dublin, Ireland. Interdisciplinary PhD co-supervised by Prof. Marina Lynch and Prof. Kingston Mills.
Postgraduate Certificate in Innovation and Entrepreneurship, Trinity College Dublin, Ireland.
B.Sc. (Mod), Trinity College Dublin, Ireland.
Natural Science with a moderatorship in Neuroscience.
2024 EU Joint Programme - Neurodegenerative Disease Research (JPND) (2024-2027)
2024 Alzheimer’s Association Research Fellowship (2024-2027)
2024 Career Development Fellowship, DZNE
2023 TravelAward from Demenzhilfe to attend AAIC, The Netherlands
2023 Deutsche Demenzhilfe Research Grant (2023-2024)
2022 Travel Award from the Alzheimer’s Association to attend AAIC, San Diego, USA
2022 Award from the ImmunoSensation 2 Cluster of Excellence, Germany to attend the European Macrophage and Dendritic Cell Society Meeting
2022 Deutsche Demenzhilfe Research Grant (2022-2023)
2021 Alzheimer Forschung Initiative (AFI) Research Grant (2021- 2023)
2020 Immunosensation PostDoc Innovation Fund Research Grant
2018 Travel Award from the ImmunoSensation 2 Cluster of Excellence, Germany to attend aSummer School on Neuroinflammation, Spain
2017 Travel Award from AFIto attend the European Meeting on Glial Cells in Health and Disease, Scotland
2016 Travel Award from the ImmunoSensation 2 Cluster of Excellence, Germany to attend a Summer School on Neuroinflammation, Spain
2014 Travel Award from the German Multiple Sclerosis Society to attend the International Society of Neuroimmunology meeting (ISNI), Mainz, Germany
2013 Travel Award from the British Society of Immunology (BSI) to attend the BSI Congress, Liverpool, UK
2013 Oral Presentation Prize, Frontiers in Neurology Conference
2012 Poster Presentation Prize, Neuroscience Ireland Conference
2019-2023 PostDoc committee member of the Bonn School of Advanced Studies in Immunology
2013-2014 CommitteeMember, Neuroscience Ireland Early-Career Researchers Committee, Co-organizer for the Young Neuroscientists Symposium 2014
2012-2014 Society Secretary, Dublin University Neuroscience Society (NeuroSoc)
