Dagmar Wachten  Publications

ScienceTeamPublicationsAlumni


‍All Publications

Selected publications

Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function.

Khani S, Topel H, Kardinal R, Tavanez AR, Josephrajan A, Larsen BDM, Gaudry MJ, Leyendecker P, Egedal NM, Güller AS, Stanic N, Ruppert PMM, Gaziano I, Hansmeier NR, Schmidt E, Klemm P, Vagliano LM, Stahl R, Duthie F, Krause JH, Bici A, Engelhard CA, Gohlke S, Frommolt P, Gnad T, Rada-Iglesias A, Pradas-Juni M, Schulz TJ, Wunderlich FT, Pfeifer A, Bartelt A, Jastroch M, Wachten D*, Kornfeld JW*.

Nat Metab. 2024 Jun;6(6):1053-1075

A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation

Hansen JN, Kaiser F, Leyendecker P, Stüven B, Krause JH, Derakhshandeh F, Irfan J, Sroka TJ, Preval KM, Desai PB, Kraut M, Theis H, Drews AD, De-Domenico E, Händler K, Pazour GJ, Henderson DJP, Mick DU, Wachten D

EMBO Rep. 2022 Aug 3;23(8):e54315

AdipoQ-a simple, open-source software to quantify adipocyte morphology and function in tissues and in vitro

Sieckmann K, Winnerling N, Huebecker M, Leyendecker P, Juliana Silva Ribeiro D, Gnad T, Pfeifer A, Wachten D, Hansen JN

Mol Biol Cell. 2022 Oct 1;33(12):br22

Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium

Hansen JN, Kaiser F, Klausen C, Stüven B, Chong R, Bönigk W, Mick DU, Möglich A, Jurisch-Yaksi N, Schmidt FI, Wachten D.

Elife. 2020 Jun 24;9:e57907. doi: 10.7554/eLife.57907.

A novel biosensor to study cAMP dynamics in cilia and flagella

Mukherjee S, Jansen V, Jikeli JF, Hamzeh H, Alvarez L, Dombrowski M, Balbach M, Strünker T, Seifert R, Kaupp UB, Wachten D.

Elife. 2016 Mar 22;5:e14052. doi: 10.7554/eLife.14052.

Controlling fertilization and cAMP signaling in sperm by optogenetics

Jansen V, Alvarez L, Balbach M, Strünker T, Hegemann P, Kaupp UB, Wachten D.

Elife. 2015 Jan 20;4:e05161. doi: 10.7554/eLife.05161.

Selected Reviews

The neuronal cilium - a highly diverse and dynamic organelle involved in sensory detection and neuromodulation

N. Jurisch-Yaksi, D. Wachten, J. Gopalakrishnan

Trends Neurosci . 2024 May;47(5):383-394.

Emerging principles of primary cilia dynamics in controlling tissue organization and function

Gopalakrishnan J, Feistel K, Friedrich BM, Grapin-Botton A, Jurisch-Yaksi N, Mass E, Mick DU, Müller RU, May-Simera H, Schermer B, Schmidts M, Walentek P, Wachten D.

EMBO J. 2023 Nov 2;42(21):e113891.

Primary cilia and their effects on immune cell functions and metabolism: a model

Ernesto Picon-Galindo, Eicke Latz, Dagmar Wachten,

Trends Immunol. 2022 May;43(5):366-378

Signal transduction in primary cilia - analyzing and manipulating GPCR and second messenger signaling

Wachten D, Mick DU.

Pharmacol Ther. 2021 Aug;224:107836. doi: 10.1016/j.pharmthera.2021.107836

The BBSome: a nexus controlling energy metabolism in the brain

Blaess S, Wachten D.

J Clin Invest. 2021 Apr 15;131(8):148903. doi: 10.1172/JCI148903.

Elucidating cyclic AMP signaling in subcellular domains with optogenetic tools and fluorescent biosensors

Klausen C, Kaiser F, Stüven B, Hansen JN, Wachten D.

Biochem Soc Trans. 2019 Dec 20;47(6):1733-1747. doi: 10.1042/BST20190246.

How to control cyclic nucleotide signaling by light

Jansen V, Jikeli JF, Wachten D.

Curr Opin Biotechnol. 2017 Dec;48:15-20. doi: 10.1016/j.copbio.2017.02.014. Epub 2017 Mar 10.

Institute of Innate Immunity
University Hospital Bonn
Biomedical Center (BMZ 2)
Building 12
2G
Venusberg-Campus 1
53127 Bonn, Germany

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