Florian Schmidt Lab Publications

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Publication metrics Florian Schmidt
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Selected publications

Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application

Lisa D J Schiffelers, Yonas M Tesfamariam, Lea-Marie Jenster, Stefan Diehl, Sophie C Binder, Sabine Normann, Jonathan Mayr, Steffen Pritzl, Elena Hagelauer, Anja Kopp, Assaf Alon, Matthias Geyer, Hidde L Ploegh, Florian I Schmidt

Nat Commun . 2024 Sep 26;15(1):8266. doi: 10.1038/s41467-024-52110-1.

P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

Jenster LM, Lange KE, Normann S, vom Hemdt A, Wuerth JD, Schiffelers LDJ, Tesfamariam YM, Gohr FN, Klein L, Kaltheuner IH, Ebner S, Lapp DJ, Mayer J, Moecking J, Ploegh HL, Latz E, Meissner F, Geyer M, Kümmerer BM, Schmidt FI

J Exp Med 2 January 2023; 220 (1): e20220837

Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape

Koenig PA, Das H, Liu H, Kümmerer BM, Gohr FN, Jenster LM, Schiffelers LDJ, Tesfamariam YM, Uchima M, Wuerth JD, Gatterdam K, Ruetalo N, Christensen MH, Fandrey CI, Normann S, Tödtmann JMP, Pritzl S, Hanke L, Boos J, Yuan M, Zhu X, Schmid-Burgk JL, Kato H, Schindler M, Wilson IA, Geyer M, Ludwig KU, Hällberg BM, Wu NC, Schmidt FI.

Science. 2021 Feb 12;371(6530):eabe6230. doi: 10.1126/science.abe6230. Epub 2021 Jan 12.

Phenotypic Lentivirus Screens to Identify Antiviral Single Domain Antibodies

Schmidt FI.

Methods Mol Biol. 2018;1836:139-158. doi: 10.1007/978-1-4939-8678-1_7.

Selected Reviews

From atoms to physiology: what it takes to really understand inflammasomes

Schmidt FI.

J Physiol. 2019 Nov;597(22):5335-5348. doi: 10.1113/JP277027. Epub 2019 Nov 4.

Institute of Innate Immunity
University Hospital Bonn
Biomedical Center (BMZ 2)
Building 12
2G
Venusberg-Campus 1
53127 Bonn, Germany

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